WELCOME TO CHATEAU DU MER BEACH RESORT

If this is your first time in my site, welcome! Chateau Du Mer is a beach house and a Conference Hall. The beach house could now accommodate 10 guests, six in the main floor and four in the first floor( air conditioned room). In addition, you can now reserve your vacation dates ahead and pay the rental fees via PayPal. I hope to see you soon in Marinduque- Home of the Morions and Heart of the Philippines. The photo above was taken during our first Garden Wedding ceremony at The Chateau Du Mer Gardens. I have also posted my favorite Filipino and American dishes and recipes in this site. Some of the photos and videos on this site, I do not own, but I have no intention on the infringement of your copyrights!

Marinduque Mainland from Tres Reyes Islands

Marinduque Mainland from Tres Reyes Islands
View of Marinduque Mainland from Tres Reyes Islands-Click on photo to link to Marinduque Awaits You

Sunday, June 15, 2025

Is Pain Tolerance A Genetic Disorder?

This posting is inspired from the story of a fellow THD resident that most of the time, she does not feel pain at all. I did some research and here's what I learned. 

Pain tolerance has both genetic (inherited) and environmental components. Some people are naturally more tolerant of pain due to genes that affect nerve signaling, endorphin production, or inflammatory responses. Others may develop higher pain tolerance over time due to lifestyle, chronic pain exposure, psychological conditioning, or cultural norms.

Inherited Conditions: Congenital Insensitivity to Pain

The case you mention — someone who does not feel pain at all — is not normal and likely involves a rare genetic disorder called:

Congenital Insensitivity to Pain (CIP) or Congenital Analgesia

Key features:

  • The individual cannot feel physical pain but may have normal touch and temperature sensation.

  • Caused by mutations in genes like SCN9A, which affect sodium channels essential for pain signal transmission.

  • Extremely rare, with only a few hundred cases worldwide.

  • People with CIP are at high risk of injury, burns, fractures, or infections because they don't receive the pain signals that normally protect the body.

Is Pain Tolerance Heritable?

Yes — but in degrees, not absolutes.

  • Studies, including twin studies, suggest that 30–60% of variability in pain sensitivity can be attributed to genetic factors.

  • Specific genes influence:

    • Pain perception (e.g., COMT gene affects dopamine breakdown)

    • Opioid receptor sensitivity

    • Inflammatory response

Summary

  • Yes, pain tolerance is partly inherited.

  • Complete lack of pain is abnormal and very rare — most likely due to CIP, a serious genetic disorder.

  • If you know someone like this, it's worth encouraging medical consultation, as early diagnosis can prevent injury and complications.

Here is a reflective short story inspired by my interest in inherited traits and the rare condition of pain insensitivity:


"The Girl Who Never Winced"
A Reflective Story on Pain, Inheritance, and the Gift of Feeling

I once met a girl who never flinched. She was seven when she fell off her bike and got up laughing, blood dripping down her knee like strawberry syrup. Her mother rushed toward her, panic in her voice, but the girl waved her off. “It doesn’t hurt,” she said. And it didn’t.

That girl’s name was Lila. By the time she was nine, she’d broken her arm falling from a tree and didn’t cry. She only noticed something was wrong when she couldn’t move her fingers. At twelve, she burned her hand on a stove and watched the skin blister without a tear, without a scream. Pain, the guardian we all wish away, had never made her acquaintance.

Doctors later diagnosed her with Congenital Insensitivity to Pain, a rare genetic condition. No warning system. No signal of danger. Her nerves were silent even when her body was screaming. Her parents, once relieved that their daughter was “tough,” now lived in quiet dread, always watching, always wondering what injury might go unnoticed next.

And yet, Lila was full of life. She danced, she climbed, she wrote poems about rain and resilience. What she lacked in sensation, she made up for in spirit. She once told me, “I don’t know what pain feels like, but I see it in others. I feel it when my mom cries. I feel it when someone I love is hurting. That’s how I understand it — through them.”

That conversation stayed with me. It made me reflect on the invisible threads of inheritance — what we pass on in blood, and what we pass on in spirit. Most of us inherit pain as a protective mechanism. Some inherit a body that forgets how to feel it. But all of us inherit the capacity to witness, to empathize, to be moved by another’s suffering.

Pain, as unpleasant as it is, teaches us our limits. It humbles us, slows us down, protects us from harm. It is not the enemy — it is the whisper of warning, the nudge toward healing.

Lila is grown now, working in medical research. She studies pain not because she knows it, but because she doesn’t. “It’s my way of learning what I never felt,” she says. “And helping others who feel it too much.”

Her story reminds me that in a world where we seek to escape pain, sometimes it's the ability to feel — both joy and sorrow — that makes us truly alive.


Here are a few quote options that resonate beautifully with the story’s theme  above— 

1. “Pain insists upon being attended to. God whispers to us in our pleasures, speaks in our consciences, but shouts in our pains.”— C.S. Lewis

2. “The wound is the place where the Light enters you.”— Rumi

3.“To hurt is as human as to breathe. But to feel another’s hurt is to love.”— Anonymous

4.“We can ignore even pleasure. But pain demands to be felt.”— John GreenThe Fault in Our Stars

5.“Not feeling pain is not a gift — it is the absence of a teacher.” Inspired by the story above

The above article and story was created with the help of AI technology.  

Finally here are 50 euphemisms and Dysphemisms


The one I really like is that I am chronologically gifted instead of old and Domestic Engineers instead of housekeepers or homemakers and a Senior Citizen instead of old person.

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