In experiments published in the journal Nature Metabolism, this compound helped eliminate senescent cells, which are aged cells that stop functioning properly and contribute to the body's deterioration. By reducing their presence, the mice maintained better mobility and lived slightly longer than usual.
Based on these results, the Chinese company Lonvi Biosciences is developing a pill based on PCC1. The company claims its goal is to create a treatment that promotes longevity, even up to 150 years; however, independent experts caution that, for now, everything is in an experimental phase. Although the animal studies are encouraging, there are no human clinical trials demonstrating that this compound can significantly extend human lifespan.
- "The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice", Nature Metabolism, DOI:10.1038/s42255-021-00491-8

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